It is an autosomal recessive disease; it is one of the rare eye diseases in which night blindness and other vision problems occur. It is rare that it directly affects the choroid and the retina, where an enzyme: ornithine ketoacid aminotransferase is present, has deficiencies and is unable to complete its functions in the ocular organ.

Treatment: is based on a diet:

• Increase the doses Vit B6 (pyridoxine) + proline

• Decrease arginine intake

• Take Lysine and alpha-aminoisobutyric acid (which increase ornithine renal elimination).