It is a rare and bilateral disease, although it means absence of iris, there is always a rudimentary iris. There may be total or partial hypoplasia of this and accompanied by hypoplasia of the fovea or the optic nerve, generating a congenital sensory nystagmus. Visual acuity is 20% or worse, and cataracts, glaucoma, and corneal opacification from limbic insufficiency may appear, which can worsen vision.

Treatment: The use of cosmetic contact lenses is an option, but current ocular microsurgery allows in many cases to perform the reconstruction of the iris and pupil, in partial defects. With total or subtotal defects, it is possible to use 90 ° or 180 ° annular implants that form a complete iris. The most innovative is the Artificial Iris, a flexible iris with a personalized color according to the photograph, which allows its implantation without the need for sutures.